Sialic acid-binding lectin
WebApr 10, 2024 · Sialic acid-binding immunoglobulin-like lectins (Siglecs) are a family of immunomodulatory receptors expressed in hematopoietic lineages . In humans, 14 Siglecs have been identified, each containing an outmost (N-terminal) V-set Ig domain with a sialic acid binding site, and the majority of these receptors possess inhibitory activity. WebSialic Acid Binding Ig Like Lectin 1 (SIGLEC1) Polyclonal Antibody (Human), Biotinylated. Sialic Acid Binding Ig Like Lectin 1 (SIGLEC1) Polyclonal Antibody (Human), Biotinylated (Opinii: 0) Numer katalogowy: 338-4-PAA966Hu02 …
Sialic acid-binding lectin
Did you know?
WebSep 14, 2024 · [0126] Without being bound by theory, Applicants postulate that glycopeptides comprising sialic acid structures are similar to structures on the surface of tumor cells (e.g., melanoma tumor cells, CRC) and therefore activate the anti-cancer activity of immune cells (e.g., T cells) via binding to lectins on the immune cell surface (i.e., … WebRazi, N.; Varki, A., Cryptic sialic acid binding lectins on human blood leukocytes can be unmasked by sialidase treatment or cellular activation. Glycobiology 1999, 9, 1225-1234.
WebSialic acid-specific lectin from Tritrichomonas mobilensis A new endothelial cell ... D.E.; Hampton, R.W.; Gardner, W.A.Jr 1994: Immunological characterization of a sialic acid binding lectin-adhesion molecule in Tritrichomonas mobilensis Abstracts of the General Meeting of the American Society for Microbiology 94: 55. Babál, P.; Pindak, F.F ... WebThe main aim of this study was to apply an alternative assay protocol to the immunoassay-based analysis of this disease by employment of sialic acid recognizing lectin Sambucus nigra agglutinin (SNA) to glycoprofile serum samples. To our best knowledge this is the first study describing direct lectin-based glycoprofiling of serum SSc samples.
WebNov 25, 2008 · Function. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may … Web1)Wash lectin agarose column to remove unbound proteins with HEPES- or TRIS-Buffered saline (HBS, TBS), pH 7.5, until OD280nm reaches background level. 2)Apply Glycoprotein …
WebWe found that a sialic acid-binding lectin (SABL) from bullfrog egg bears a remarkable degree of similarity with human angiogenin and the pancreatic ribonucleases (EC 3.1.27.5). Based on (1) the conservation of several disulfide bond-forming cysteines, (2) a cluster of nonpolar residues, and (3) a number of active-site residues of bovine ribonuclease, we …
WebPreferred lectins applied in the context of the present invention are described herein. Also included by the term "lectin" are Siglecs (sialic acid-binding immunoglobulin-like lectins). Notably, the term "lectin" when used herein also refers to glycan-binding antibodies. porsche personalized license plateWebJan 13, 2024 · Sialic acid-binding immunoglobulin-like lectin-15 (Siglec-15) is a new immune checkpoint molecule and its role of primary central nervous system lymphoma (PCNSL) … irish club of waWebSialic acid-binding Ig-like lectin 12, or Siglec-XII, is a protein that in humans, is encoded by the SIGLEC12 gene. [3] [4] [5] Sialic acid -binding immunoglobulin-like lectins ( SIGLECs) … irish cnc filesWebThe K8 monoclonal antibody specifically recognizes Sialic acid-binding Ig-like lectin 9 (Siglec-9) which is also known as CD329. Siglec-9 (CD329) is a single-pass type I … irish club westonWebThe hemagglutination of purified lectin was inhibited by N-acetylneuraminic acid but not by N-glycolylneuraminic acid, even at a concentration of 100 mm. Bovine submaxillary mucin, which contains mainly 9-O-acetyl- and 8,9 di-O-acety-N-acetyl neuraminic acid was the most potent inhibitor of the lectin. irish club tottenhamWebアズワンの【AXEL】84-2070-14 Siglec 15, CT (Siglec 15, CD33L3, Sialic acid-binding Ig-like lectin 15, CD33 antigen-like 3) (PE) 200ul 041736-PEのコーナーです。AXELは研究開発、医療介護、生産現場、食品衛生など幅広い分野に750万点以上の品揃えでお応えする商品サイト。3000円以上ご注文で送料無料。 irish club winnipegWebSialic acid-specific lectin from Tritrichomonas mobilensis A new endothelial cell ... D.E.; Hampton, R.W.; Gardner, W.A.Jr 1994: Immunological characterization of a sialic acid … irish club yarmouth ma