WebThe aim of the PANDA randomised controlled trial is to investigate the severity and duration of depressive symptoms that are associated with a clinically important response to SSRI antidepressants in people with depression. We will carry out a randomised controlled trial comparing sertraline to placebo in individuals with depression whom the ... WebApr 4, 2024 · The PANDA trial was a multicentre, double-blind, randomized clinical trial in UK primary care comparing the SSRI sertraline with placebo for depression and anxiety.
Sertraline in primary care: comments on the PANDA trial – …
WebNov 27, 2024 · In brief, PANDA is a randomised, double-blind, placebo-controlled trial in which participants are individually randomised to sertraline or placebo. WebMar 1, 2009 · A randomised controlled trial assessing the severity and duration of depressive symptoms associated with a clinically significant response to sertraline versus placebo, in people presenting to primary care with depression (PANDA trial): study protocol for a randomised controlled trial. thus saith the lord who created you
The clinical effectiveness of sertraline in primary care and the role ...
WebJan 1, 2024 · The results from the PANDA trial showed that sertraline is well-tolerated, at least with short-term use, and this finding is consistent with a recent umbrella review of meta-analyses. We did not investigate long-term antidepressant use but are aware of other studies investigating these questions. WebNov 1, 2024 · Sertraline is unlikely to reduce depressive symptoms within 6 weeks in primary care but we observed improvements in anxiety, quality of life, and self-rated mental health, which are likely to be clinically important. ... In the PANDA trial, 115 (46%) participants on sertraline thought they were taking the active drug at 6 weeks compared … WebMethods: The PANDA study was a pragmatic, multicentre, double-blind, placebo-controlled randomised trial of patients from 179 primary care surgeries in four UK cities (Bristol, … thus saith the scriptures