He4分子量

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http://commercial.dxy.cn/article/483173 WebMay 19, 2016 · Ovarian cancer is a common malignancy of the female reproductive system. Tumor markers serve as tools in the diagnosis of the disease. The aim of the present study was to determine the diagnostic …

精确诊断卵巢癌的血清标志物： HE4+CA125 - 丁香园 - DXY.cn

WebApr 13, 2024 · View Atlanta obituaries on Legacy, the most timely and comprehensive collection of local obituaries for Atlanta, Georgia, updated regularly throughout the day … WebApr 7, 2024 · Atlanta, city, capital (1868) of Georgia, U.S., and seat (1853) of Fulton county (but also partly in DeKalb county). It lies in the foothills of the Blue Ridge Mountains in … how old is an older adult

The diagnostic value of human epididymis protein 4 for ... - Nature

Web专家点评. HE4作为一种新型的卵巢肿瘤标志物，其价值在临床中的应用被广泛认可，尤其是与CA125的联合应用。. 在此病例中，本科室临床医生也从未见过如此高的HE4结果，在妇科可能引起HE4升高的疾病当中，即使是卵巢恶性上皮肿瘤也不会有如此惊人的数值，更 ... WebHuman epididymis protein 4 (HE4) belongs to the family of whey acidic four-disulfide core (WFDC) proteins. Currently, the biologic function of HE4 is unknown. HE4 has been … WebHE4的中文全称为人附睾蛋白4，为一种比较特异性的卵巢上皮性肿瘤的肿瘤标志物。由卵巢上皮性肿瘤细胞所分泌的糖蛋白，分子量在25kDa左右。HE4主要产生在上皮性卵巢癌 … how old is an oak tree

肿瘤标志物科普系列--HE4升高原因分析 - 知乎 - 知乎专栏

WebMar 6, 2024 · HE4也称乳清酸性蛋白 (whey acidicprotein, WAP)4-二硫化物核心域蛋白2,是Kirchhoff首次从人附睾上皮成功克隆出的一种分泌型糖蛋白。. HE4 作为上皮性卵巢癌的肿瘤标志物已经被美国食品药品监督管理局 (FDA)批准作为监测疾病进展及复发的标志物。. HE4在鉴别盆腔肿块 ... WebMar 21, 2005 · Abstract. Among the genes most commonly identified in gene expression profiles of epithelial ovarian carcinomas (EOC) is the gene for human epididymis protein 4 (HE4). To ascertain its clinical utility, we did a comprehensive assessment of HE4 protein expression in benign and malignant ovarian and nonovarian tissues by … mercer county school calendar wvWebJan 12, 2024 · The critical value of HE4 for endometrial cancer was 52.40 mmol/L, with a sensitivity of 57.35% and a specificity of 76.38%. For different stages of EC, the critical value was 36.9 mmol/L, and the ... mercer county school schedule wv

"WAP four-disulfide core domain protein 2 - also known as Human Epididymis Protein 4 (HE4) - is a protein that in humans is encoded by the WFDC2 gene. HE4 is a tumor marker of ovarian cancer, with 80% sensitivity at a cut-off of 150 pmol/L. See more This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a … See more • Kirchhoff C (1998). "Molecular characterization of epididymal proteins". Rev. Reprod. 3 (2): 86–95. doi:10.1530/ror.0.0030086. PMID 9685187. • Kirchhoff C, Osterhoff C, Habben I, Ivell R, Kirchloff C (1990). "Cloning and analysis of mRNAs expressed specifically in the human epididymis" See more " - He4分子量

He4分子量

HE4 Blood Test Results Fully Explained - HRF

WebJan 16, 2016 · 精确诊断卵巢癌的血清标志物： HE4+CA125. 作为卵巢癌血清肿瘤标志物之一，人附睾蛋白 4（HE4）在卵巢癌的早期诊断、治疗监测及预后评估中具有重要的医学价值，在临床的应用也日益广泛。. 但在 HE4 临床使用过程中，试剂说明书提供的参考范围来源 … WebFeb 9, 2024 · 平均分子量就是在某些計算題中會讓你求某幾個物質的“平均分子量”，那樣的話就是要算平均值，就是幾個加起來再除一下。如果問的是“平均相對分子量和相對分子量 …

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WebJul 1, 2003 · Abstract. The WFDC2 (HE4) gene is amplified in ovarian carcinomas, whereas its expression in normal tissues, including ovary, is low. Although the function of the HE4 protein is unknown,it is a member of a family of stable 4-disulfide core proteins that are secreted at high levels. We therefore performed experiments to explore whether … WebFeb 15, 2024 · Methods: Luminex-based immunoassays were used to measure human epididymis protein 4 (HE4), anti-HE4 autoantibody, and HE4 Ag-AAb complexes in sera from patients with early- (n = 73) and late-stage ovarian cancers (n = 49) at the time of diagnosis and from asymptomatic women with (n = 15) or without ovarian cancer (n = …

Web単純窒息性ガス. [ ppm ] 沸点. -268.9. [ ℃ ] He ヘリウム (PDF286KB) 記載のヘリウム（He）のデータや評価に関しては、現時点で入手できた資料や情報に基づいて作成し … WebApr 1, 2024 · HE4的中文全称为人附睾蛋白4，为一种比较特异性的卵巢上皮性肿瘤的肿瘤标志物。由卵巢上皮性肿瘤细胞所分泌的糖蛋白，分子量在25kDa左右。HE4主要产生在上皮性卵巢癌、子宫内膜癌、部分肺癌，胃癌中，相较于传统的卵巢肿瘤标志物CA125，具有一定 …

WebCurrent Weather. 5:11 AM. 47° F. RealFeel® 48°. Air Quality Excellent. Wind NE 2 mph. Wind Gusts 5 mph. Clear More Details. WebNov 2, 2014 · Abstract. Human epididymis protein 4 (HE4) has received major attention as a potential tumor marker in epithelial ovarian cancer; however, evidence of significant overexpression of HE4 in several other human cancers is expanding. To assess the possible limitations or benefits of HE4 in a clinical setting, this review aims to systematically …

WebJun 15, 2013 · HE4 may serve as a useful prognostic biomarker for ovarian and endometrial cancer. Elevated levels of HE4 are associated with increases in International Federation of Gynecology and Obstetrics (FIGO) stage, grade, preoperative CA 125 levels, and residual tumor. [68] Elevated HE4 levels also correlate with the aggressiveness of ovarian …

Web碳（Carbon）是一种非金属元素，化学符号为C，在常温下具有稳定性，不易反应、极低的对人体的毒性，甚至可以以石墨或活性炭的形式安全地摄取，位于元素周期表的第二周期IVA族。碳是一种很常见的元素，它以多种形式广泛存在于大气和地壳和生物之中。拉丁语为Carbonium，意为“煤，木炭”。 how old is an old personWeb乙二胺四乙酸（EDTA）是一种有机化合物，其化学式为C10H16N2O8，常温常压下为白色粉末。它是一种能与Mg2+、Ca2+、Mn2+、Fe2+等二价金属离子结合的螯合剂。由于多数核酸酶类和有些蛋白酶类的作用需要Mg2+，故常用做核酸酶、蛋白酶的抑制剂；也可用于去除重金属离子对酶的抑制作用。 mercer county senior citizen centerWebHuman epididymis protein 4 (HE4) was first identified in the epithelium of the distal epididymis and was originally predicted to be a protease inhibitor involved in sperm maturation. 4,5 HE4 is the gene product of the WFDC2 gene that is located on chromosome 20q12-13.1. The WFDC2 gene is one of 14 homologous genes on this chromosome that … how old is an r reg vehicle