WebCytokeratin (CK) AE1/AE3 is a broad-spectrum immunohistochemical antibody cocktail that is used to identify the expression of high- and low-molecular weight keratins. Positive … WebCytokeratin pan is part of a subfamily of intermediate filament proteins that are characterized by remarkable biochemical diversity, and represented in human epithelial …
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WebNov 4, 2024 · The tumor cells co-express cytokeratin AE1/AE3 ( d ), S100 protein ( e ), and SOX10 ( f) in most cases. Myoepithelial carcinomas show similar morphologic features to myoepitheliomas, but... WebAug 16, 2016 · After confirmation of neuroendocrine differentiation, a panel of general epithelial biomarkers (cytokeratins AE1/AE3, CAM5.2, and/or CK18) is recommended to exclude a potential paraganglioma (Figs. 1 and 3). 1, 8, 16, 27 This distinction is crucial as the management of paraganglioma can differ from that of other NETs. 1, 10, 16, 27, 28 … moganshan altitude
Cytokeratin AE3 - an overview ScienceDirect Topics
WebCytokeratin (CK) AE1/AE3 is a broad-spectrum immunohistochemical antibody cocktail that is used to identify the expression of high- and low-molecular weight keratins. Positive staining is generally indicated by filamentous cytoplasmic or membranous reactivity within the cells of interest and typically implies an epithelial origin [1]. CK ... WebImmunohistochemistry: cytokeratin AE1/AE3, strongly positive diffuse nuclear staining of neoplastic cells, Ck 5/6, strongly positive nuclear cytoplasmic staining of neoplastic … The antibody cocktail binds to cytokeratin 1 - 8, 10, 14 - 16 and 19 (but not CK17 or CK18). It is therefore used as a marker of carcinomas, such as depth of invasion and metastases. For example, it is both relatively sensitive and specific for detection of breast cancer metastasis to sentinel lymph nodes. It may cross-react with GFAP, leading to aberrant staining of glial tumors such as ependymoma, gl… mogan princess \\u0026 beach club tripadvisor