Cytohesin-1
WebJun 6, 2000 · Cytohesin-1 comprises an N-terminal coiled-coil domain, which may aid in oligomerization, a central Sec7 domain and a C-terminal module including the pleckstrin … WebAug 18, 2003 · Cytoplasmic exchange factors for ARFs have been identified; they are called cytohesin-1 , ARNO (cytohesin-2) and GRP-1 (cytohesin-3) . Cytohesin-1 is a 47 …
Cytohesin-1
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WebThis gene encodes a member of the cytohesin (CYTH) family, formerly known as the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. Cytohesin family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain.
WebKolanus W, et al. alphaLbeta2 integrin/LFA-1 binding to ICAM-1 induced by cytohesin-1 a cytoplasmic regulatory molecule. Cell 86: 233-242, 1996. PubMed: 8706128 ... Jang SI, et al. Activator protein 1 activity is involved in the regulation of the cell type-specific expression from the proximal promoter of the human profilaggrin gene. J. Biol ... WebCytohesin proteins are ubiquitous and have been implicated in several functions including cell spreading and adhesion, chemotaxis, protein trafficking, and cytoskeletal …
WebCytohesin-2 is enriched in the perisynapse on the postsynaptic membrane of dorsal horn neurons and forms a protein complex with mGluR5 in the spinal cord. Central nervous system-specific cytohesin-2 conditional knockout mice exhibited reduced mechanical allodynia in inflammatory and neuropathic pain models. WebJun 6, 2000 · Cytohesin-1 comprises an N-terminal coiled-coil domain, which may aid in oligomerization, a central Sec7 domain and a C-terminal module including the pleckstrin homology (PH) domain and a polybasic region. Cytohesin-1 specifically binds to the intracellular domain of the β-2 integrin chain and has been implicated in the functional …
WebCytohesin 1 Antibody (MA1-060) in ICC/IF Immunofluorescence analysis of Cytohesin 1 was done on 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature.
WebJun 4, 2009 · Cytohesin-1 is up-regulated in human Mo-DCs during maturation, and is efficiently silenced by RNAi in both human and murine DCs. Western blot analysis shows that cytohesin-1 expression is up-regulated in human monocyte-derived dendritic cells (Mo-DCs) upon maturation induced by LPS (1 μg/mL)/TNF alpha (50 ng/mL; panel A lanes … high school syllabus in usaWebJul 26, 2004 · The considerable sequence homology of cytohesin-1 and ARNO/cytohesin-2 (Fig. 1 A) set against the significant differences in their biological function demands further explanation and highlights the need to clearly differentiate between these related regulatory factors.We set out to obtain specific inhibitors of these proteins that can discriminate … how many countries have africaWebCytohesin-1 is required for Schwann cell migration and that phosphorylation of cytohesin-1 at the Tyr-382 position is important for migration. Phosphorylation of cytohesin-1 by Fyn is required for initiation of myelination and the extent of myelination during development. high school syllabus sampleWebJul 7, 1998 · Cytohesin-1 (B2–1) is a guanine nucleotide exchange factor for human ADP ribosylation factor (Arf) GTPases, which are important for vesicular protein trafficking and coatamer assembly in the cell. Cytohesin-1 also has been reported to promote cellular adhesion via binding to the β2 integrin cytoplasmic domain. high school synWebOrthologs 1; Homo sapiens (human): CYTH1 (cytohesin 1) HGNC: EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Treefam: Mus musculus (house mouse): Cyth1 (cytohesin 1) Transitive Ortholog Pipeline: Transitive Ortholog Pipeline: Chinchilla lanigera (long-tailed chinchilla): Cyth1 (cytohesin 1) Transitive Ortholog Pipeline: … high school syllabus template mathWebMar 21, 2024 · CYTH1 (Cytohesin 1) is a Protein Coding gene. Diseases associated with CYTH1 include Intellectual Developmental Disorder With Short Stature And Behavioral … how many countries have banned human cloningWebCYTIP cytohesin 1 interacting protein [ (human)] Gene ID: 9595, updated on 29-Mar-2024 Summary The protein encoded by this gene contains 2 leucine zipper domains and a putative C-terminal nuclear targeting signal, but does not have any hydrophobic regions. This protein is expressed weakly in resting NK and T cells. high school syllabus history