WebMar 1, 2024 · Results. Chloroquine combined with cisplatin significantly inhibited HNE1 cell proliferation in vitro and the growth of HNE1 cell-derived tumor in nude mice as compared with cisplatin alone (P < 0.01). In cultured HNE1 cells, inhibition of the expression of miR129 significantly promoted autophagy and up-regulated P-gp expression (P < 0.01); … WebSep 21, 2016 · 3ma和cq抑制的自噬有什么不同. #热议# 哪些癌症可能会遗传给下一代?. 自噬(autophagy)是由 Ashford 和 Porter 在 1962 年发现细胞内有“自己吃自己”的现象后 …
自噬 - selleck
WebChloroquine (NSC-187208, Aralen, CHQ, CQ)是抗疟药和自噬及溶酶体 autophagy/lysosome 的抑制剂。Chloroquine 还可抑制 Toll-like receptor-9 (TLR9) 蛋白的表达。Chloroquine … WebDec 10, 2024 · Bafilomycin A1(巴佛洛霉素 A1),CAS:88899-55-2,是一种大环内酯类抗生素,特异性,可逆的H+-ATPase(V-ATPase)抑制剂,IC50 值是 4-400 nmol/mg,在晚期也被用作自噬抑制剂。巴佛洛霉素A1阻断自噬体-溶酶体融合,也可以抑制细胞溶酶体中的酸化和蛋白质降解,具有诱导调亡的作用 armani bags dubai
【讨论帖】Autophagy(自噬) - 经验共享 - 分析测试百科
Web医学科研实验基础知识笔记(四):细胞自噬研究策略. 细胞自噬是指细胞在外界环境因素的影响下, 细胞利用溶酶体降解自身受损、 变性或衰老的大分子物质以及细胞器的自我消化过程。. 自噬是细胞的一种自我保护机制, 广泛存在于真核细胞内, 在调节 ... WebOct 28, 2016 · Often, no lower than a Cq of 13 or 14 is best on the concentrated end (for hydrolysis probe-based assays due to excessive fluor accumulation on the concentrated end skewing the Cq values downward ... Web3-Methyladenine (3-MA) is used to inhibit and study the mechanism of autophagy (lysosomal self-degradation) and apoptosis under various conditions. 3-MA inhibits autophagy by blocking autophagosome formation via the inhibition of type III Phosphatidylinositol 3-kinases (PI-3K). For use as an autophagy inhibitor, 3-MA is … bal tdv