WebMoreover, DSF sensitized ovarian cancer cells to cisplatin treatment and enhanced cisplatin-induced apoptosis, both in SDC and MDC. In the present studies, we have used a quantitative method to determine synergism or antagonism of DSF in chemotherapy drug treatment. Three pairs of two-drug combinations and a three-drug combination were … WebSilencing STING by siRNA rescued HaCaT cells from UVB or cisplatin-induced apoptosis. NF-κB, one of the major downstream components of STING pathway, which usually regulates the classical STING apoptotic pathway, was translocated to nucleus in the HaCaT cells irradiated with UVB. This translocation was attenuated by STING silencing.
Cisplatin-induced apoptosis proceeds by caspase-3 ... - PubMed
WebThe chemotherapeutic drug cisplatin elicits cytotoxicity causing renal tubular cell death, but its executing mechanisms of action are versatile and elusive. Here, we show that cisplatin induces renal tubular cell apoptosis and ferroptosis by … WebNov 7, 2024 · Cisplatin binds to DNA and induces DNA-damage culminating in mitochondria-mediated apoptosis. Interestingly, mitochondrial DNA is critically affected … magnifican
Cisplatin-induced apoptosis in auditory cells: role of death recep…
WebCisplatin (cis-diamminedichloroplatinum; CDDP) 1 is a potent inducer of growth arrest and/or apoptosis in most cell types and is among the most effective and widely used chemotherapeutic agents employed for … WebNov 3, 2024 · Purpose The nephrotoxicity caused by cisplatin severely limits the application and affects related platinum-based therapeutics. Neferine is a dibenzylisoquinoline alkaloid extracted from a Chinese … WebThis study investigated non-targeted metabolomic analysis on ABs and medium from apoptotic HK-2 cells induced with cisplatin or exposure to UV light. ... We did not mean that these differences will result in differences in the extension of apoptosis induced by ABs because we knew from our previous work published in Biochimica et Biophysica … magnifica evo vs lattego