WebCHSY1 was secreted from patients' fibroblasts and was required for synthesis of chondroitin sulfate moieties. Noticeably, its absence triggered massive production of JAG1 and subsequent NOTCH activation, which could only be reversed with a wild-type but not a Fringe catalytically dead CHSY1 construct. WebJan 1, 2014 · The Fringe-like domain in CHSY1 shares 47 % amino acid similarity with Fringe, and it also has the key DXD motif. Modulation of Notch signaling by CHSY1 via its DXD motif may provide new insight into the interaction mechanisms between myeloma cells and their bone marrow microenvironment.
CHSY1 promoted proliferation and suppressed apoptosis in
WebCHSY1 Antibody (14420-1-AP) in IHC (P) Immunohistochemistry of paraffin-embedded human lung cancer using 14420-1-AP (CHSY1 antibody) at dilution of 1:100 (under 40x lens). Product Details Product Specific Information WebDriving Directions to Tulsa, OK including road conditions, live traffic updates, and reviews of local businesses along the way. philosopher\\u0027s y7
Full article: CHSY1 is upregulated and acts as tumor promotor in ...
WebDefects in CHSY1 cause temtamy preaxial brachydactyly syndrome (TPBS; MIM:605282), a syndrome characterized by multiple congenital anomalies, mental retardation, sensorineural deafness, growth retardation and bilateral symmetric digital anomalies mainly in the form of preaxial brachydactyly (literally, shortness of fingers and toes) and … WebChondroitin sulfate synthase 1 is an enzyme that in humans is encoded by the CHSY1 gene. [5] [6] CHSY1 synthesizes chondroitin sulfate, a glycosaminoglycan expressed on the … WebMar 31, 2016 · View Full Report Card. Fawn Creek Township is located in Kansas with a population of 1,618. Fawn Creek Township is in Montgomery County. Living in Fawn … philosopher\\u0027s y4