WebCDH6. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. WebJul 22, 2024 · Glioma is the most malignant cancer of the central nervous system. There are various therapies for treating gliomas, but their outcomes are not satisfactory. Therefore, new targets for glioma treatment are needed. This study examined the cadherin-6 (CDH6) expression in gliomas using The Cancer Genome Atlas and Chinese Glioma Genome …

CDH6 Gene - Somatic Mutations in Cancer - Wellcome Sanger …

WebNational Center for Biotechnology Information We analyzed the clinical pathologic data relating to 343 patients with GC derived from TGCA, including the patients’ age, sex, clinical stage, histological grade, and tumor-lymph node-metastasis (TNM) classification. As shown in Fig. 5a, the expression of CDH6 was only significantly associated with the T stage TNM … See more According to TCGA, CDH6 was highly expressed in 343 GC tissues as compared to the 30 normal tissues (P = 2.16e−09, Fig. 1a) and in 25 … See more To evaluate the diagnostic value of CDH6, the receiver operating characteristic (ROC) curve was constructed using gene expression data from … See more To analyze the biological characteristics shared by tissue samples displaying different CDH6 expression levels and predict the functions and pathways in which CDH6 may be involved, we performed the GSEA … See more As shown in Fig. 6a, high expression of CDH6 was closely associated with poor overall survival (P < 0.01). This relationship was … See more tara m wilson

CDH6 as a prognostic indicator and marker for chemotherapy in

WebThe gene view histogram is a graphical view of mutations across CDH6. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to the left. WebCDH6 preferentially bound to αIIbβ3 integrin, a platelet receptor scarcely expressed in cancer cells, and this interaction was mediated through the cadherin Arginine-glycine-aspartic acid (RGD) motif. Furthermore, CDH6 and CDH17 were found to interact with α2β1 in αIIbβ3 low cells. Transient silencing of CDH6, ITGA2B, or ITGB3 genes ... WebSep 12, 2013 · In A549 lung cancer cell line CDH6 was expressed and induced upon TGF-β treatment at levels comparable to the thyroid tumor cell lines . These results suggest that CDH6 expression is tissue specific and the ability of TGF-β to target this gene is common to other types of tumor. Cell line Nthy.ori 3.1 B-CPAP TPC1 WRO ... taran123